WASHINGTON, D.C. — A new website by the White House to reduce prescription prices for Americans is officially up and running.
For millions of Americans, picking up a prescription has become a monthly financial gamble — especially for high-cost brand-name drugs.
Now, the Trump administration says it has a new tool to bring those prices down: TrumpRx.gov, a website launched this week that offers discounts on 40 of the most popular and expensive branded medications in the country.
The launch includes drugs made by the first five manufacturers to reach what the administration calls Most Favored Nation (MFN) pricing agreements — with companies including AstraZeneca, Eli Lilly, Pfizer and others.
“We’re taking the lowest price paid for drugs. We will pay equal to whatever the lowest price- anywhere in the world- that’s the price that you’re going to be paying. It’s a tremendous reduction,” President Trump said.
The White House says the site is designed to be simple — allowing patients with valid prescriptions to access savings through printable or mobile coupons, or through discount channels created by drugmakers and built directly into the website.
Among the most notable reductions are for GLP-1 medications — drugs used for diabetes, obesity, and heart-related conditions that have become household names. The website shows Ozempic down from more than $1,000 a month to an average of about $350 — and in some cases as low as $200, depending on dosage. Zepbound, another major weight-loss drug, shows a drop from over $1,000 to an average of $346, with some prices starting around $299. Injectable Wegovy is listed at similar levels, with the pill form dropping as low as $149 a month.
Additionally, IVF and medications for infertility show some of the most drastic discounts. Experts say those cuts matter because many IVF patients pay out of pocket, and fertility drugs can add thousands to a single cycle. According to TrumpRx.gov, the drug Gonal-F shows a decrease from $966 to as low as $168 per pen. Cetrotide is listed falling from $316 to just $22.50.
The website also lists major markdowns on other high-cost medications — including inhalers, skin treatments, insulin, and menopause medications. Bevespi Aerosphere, an inhaler used to treat chronic obstructive pulmonary disease, is discounted from $458 to $51. Eucrisa, a topical ointment for atopic dermatitis, down from $792 to $158. Duavee, a medication used to treat hot flashes and osteoporosis, shows a price cut from $202 to $30.
Some industry professionals say it serves as a “one-stop shop” connecting consumers with discounts. Many discounts have been available, but hard to access.
“It wasn’t ever easily navigable by consumers. And so I think this is a very consumer-centric approach to draw people’s attention to some of those coupons they might not have been aware of,” said Kyle McCormick, owner and founder of Blueberry Pharmacy, an independent, cost-plus model pharmacy based in Pittsburgh, Pa.
McCormick says the launch of the website could promote transparency by encouraging more direct payments for what he believes medications should actually cost.
“This is something that in the cost-plus world that we’ve been arguing for and teaching and educating on for the past six plus years of, you know, ‘This is a better option, cheaper option for providing health care and pharmacy,’” McCormick said. “It signals that there is appetite for direct pay, even for historically expensive brand options.”
The White House says additional drugs and manufacturers will be added to TrumpRx.gov in the coming months.








